Ptychography, Whole Slide Imaging & Biomedical Imaging Expertise

Consulting Expertise

Fourier Ptychography & Computational Optics

Expertise in Fourier ptychography, phase retrieval, synthetic-aperture imaging, and computational reconstruction, including system architecture, calibration, algorithm development, and optimization of resolution, field of view, and imaging throughput.

Selected Work: Ptychography at all wavelengths, Nature Reviews Methods Primers, 5, 68 (2025); Wide-field, high-resolution Fourier ptychographic microscopy, Nature Photonics, 7, 739–745 (2013).

High-Throughput Microscopy & Whole-Slide Imaging

Design and optimization of high-throughput microscopy and whole-slide imaging systems, including autofocusing, illumination, scanning and acquisition strategies, computational enhancement, and resolution-throughput optimization.

Selected Work: Autofocusing technologies for whole slide imaging and automated microscopy, Journal of Biophotonics, 11(9), (2020).

Biophotonics & Biomedical Instrumentation

Development of optical instrumentation for biological and physiological measurements, including fluorescence recording, remote focusing, motion compensation, high-speed imaging, and application-specific system design.

Selected Work: High-Throughput Functional Characterization of Visceral Afferents by Optical Recordings, Frontiers in Neuroscience, 15, 657361, (2021).

Miniaturized & Fiber-Optic Imaging

Expertise in compact, handheld, and fiber-based imaging architectures for applications constrained by size, access, or form factor, including optical design, computational reconstruction, calibration, and prototype development.

Selected Work: Ptycho-endoscopy on a lensless ultrathin fiber bundle tip, Light: Science & Applications, 13, 168, (2024).

Phase Retrieval, Quantitative & Label-Free Imaging

Development of computational imaging methods for recovering phase, structural, spectral, and biochemical information, including quantitative phase imaging, label-free imaging, and multimodal reconstruction.

Selected Work: Quantitative phase imaging via Fourier ptychographic microscopy, Optics Letters, 38(22), (2013).

Optical System Design, Calibration & Metrology

System-level consulting in optical architecture, illumination and component selection, calibration, autofocus, aberration characterization and correction, and imaging-performance optimization.

Selected Work: Full-field Fourier ptychography: spatially varying pupil modeling and rapid field-dependent aberration metrology, APL Photonics, 4, 050802, (2019).

Proudly Collaborating With

Since our founding, we have been proud to collaborate with a growing network of companies, many of them here in Connecticut, as well as partners in California, Germany, and Hong Kong. Selected collaborators are featured below.