Guoan Zheng, Ph.D.

Founder & Principal Consultant

Dr. Guoan Zheng is a Professor at the University of Connecticut and the Director of the UConn Center for Biomedical and Bioengineering Innovation. His areas of expertise include biomedical instrumentation, computational imaging, biophotonics, ptychography, microscopy, and chip-scale imaging solutions.

Dr. Zheng received his B.S. degree in Electrical Engineering from Zhejiang University in 2007, his M.S. degree in Electrical Engineering from the California Institute of Technology in 2008, and his Ph.D. in Electrical Engineering from Caltech in 2013. While at Caltech, he received the Lemelson-MIT Caltech Student Prize in 2011 for his development of chip-scale microscopy solutions and the Caltech Demetriades Thesis Prize in 2013 for his work on Fourier ptychography.

Dr. Zheng is recognized for his pioneering work in Fourier ptychography, which has been widely adopted in microscopy imaging. The technique is also featured in Introduction to Fourier Optics, 4th Edition, a widely used textbook in Fourier optics. His research has resulted in one book and more than 130 peer-reviewed publications, including work published in Nature Photonics, Nature Reviews Methods Primers, Nature Reviews Physics, Nature Communications, eLight, Nature Protocols, Light: Science & Applications, and PNAS.

His research has been cited more than 16,000 times, with an h-index of 64. Dr. Zheng has been included in the Stanford-Elsevier World's Top 2% Scientists list since 2020. His work on the multiscale aperture synthesis imager was also shortlisted for the 2026 Falling Walls Science Breakthroughs.

Dr. Zheng is a named inventor on 16 awarded patents spanning imaging, sensing, and biomedical instrumentation technologies. He is an elected Fellow of SPIE and an elected member of the Connecticut Academy of Science and Engineering. He also serves in editorial, professional, and conference leadership roles across the optics, photonics, biomedical imaging, and computational imaging communities.

Featured Publications

Nature Reviews Methods Primers (2025)

Ptychography at All Wavelengths
A comprehensive perspective on ptychographic imaging across optical, X-ray, electron, and other wavelength regimes. View Publication

Nature Reviews Physics (2021)

Concept, Implementations and Applications of Fourier Ptychography
A broad review of Fourier ptychography, covering its principles, system implementations, and applications across computational imaging. View Publication

Optics Letters (2020)

OpenWSI: A Low-Cost, High-Throughput Whole Slide Imaging System via Single-Frame Autofocusing and Open-Source Hardware
An open-source whole-slide imaging platform combining rapid autofocusing, accessible hardware, and high-throughput image acquisition. View Publication

APL Photonics (2019)

Full-Field Fourier Ptychography: Spatially Varying Pupil Modeling and Its Application for Rapid Field-Dependent Aberration Metrology
A computational approach for rapid characterization and correction of field-dependent optical aberrations across a large field of view. View Publication

Optica (2016)

Diffraction Tomography with Fourier Ptychography
An extension of Fourier ptychography to three-dimensional imaging and refractive-index reconstruction of transparent samples. View Publication

Nature Photonics (2013)

Wide-Field, High-Resolution Fourier Ptychographic Microscopy
The foundational demonstration of Fourier ptychographic microscopy for computationally combining wide field of view with high-resolution quantitative imaging. View Publication